Semi-automatic benchtop filling machines for small quantities of liquid medicines
In the research and development of liquid pharmaceutical products, in the manufacture and processing of small quantities, very specific aspects of the filling process are in the foreground.
This includes the requirements of customers and authorities (e.g. the FDA), but also very specific product properties that have direct consequences on which primary packaging materials can be used and processed. All of this is extremely important for drug development.
The groninger semi-automatic tabletop system allow you to cover the entire filling and closing process. The labworx series uses the same technology, the same processing methods and components as the high-speed groninger cartridge, vial and syringe filling machines. In this way, important insights and data gained during the development process can be quickly and easily scaled up to larger filling volumes and lines.
Focus on precision
When filling liquid medicine products, manufacturers and hospital pharmacies focus on the correct composition of the active ingredients and thus on safety and effectiveness. With the labworx modules, certain critical processes that are otherwise carried out manually, such as filling, can be controlled and automated. This way you are able to achieve a high and consistent level of quality in the end product.
Due to the hygienic design, laminar airflow and compact design, the devices can be safely integrated into a range of containment systems. The modules are set up with a standard batch report, compliant with 21 CFR Part 11, and thus comply with the standard regulations for the production of small quantities.
labworx series
The new labworx benchtop machine portfolio consists of four standardized modules:
- Filling module with peristaltic pump,
- Filling module with rotary piston pump,
- Stopper setting module and
- Sealing module.
These series-built benchtop machines have an extremely short delivery time, allowing you to minimize your time-to-market cycle.
You will learn to appreciate the quickconnect technology in everyday work, which enables quick set-up and, above all, quick changeover of material and formats. The labworx modules offers you maximum flexibility.
Filler module with rotary piston pump
Specifications
- Dimension L/W/H: 450 x 560 x 700 mm
- Weight: 65 kg (depending on version)
- Connection value/frequency: 100-240V (50/60Hz)
- Filling range: 0.2-135ml
Options
- Vacuum filling
- Integration of a load cell for 100% In-Process-Control (IPC) with automatic data transfer
- Single-use rotary piston pump
- Stainless steel product tank
Objects
- All common pre-fillable packaging containers
- Other pharmaceutical bottles and containers can be set up
Application
- 5-10 containers per minute (depending on product, container and operator)
Filler module with peristaltic pump
Specifications
- Dimension: L/W/H: 450 x 510 x 700 mm
- Weight: 50 kg (depending on version)
- Connection value/frequency: 100-240V (50/60Hz)
- Filling range: 0.1-250ml
Options
- Integration of a load cell for 100% In-Process-Control (IPC)with automatic data transfer
- Single-use Equipment
- Stainless steel product tank
Objects
- All common pre-fillable packaging containers
- Other pharmaceutical bottles and containers can be set up
Application
- 5-10 containers per minute (depending on product, container and operator)
Stopper setting module
Specifications
- Dimension L/W/H: 450 x 510 x 795 mm
- Weight: 60 kg (depending on version)
- Connection value/frequency: 100-240V (50/60Hz)
Options
- Insertion tube for inserting stoppers for syringes and cartridges
- Inserting vacuum stopper for syringes and cartridges
- Setting tool for inserting stoppers for vials
- Gassing for all different stoppering methods
Objects
- All common pre-fillable packaging containers
- Other pharmaceutical bottles and containers can be set up
Output
- 5-10 containers per minute (depending on product, container and operator)
Sealing module
Specifications
-
Dimensions L/W/H: 450 x 510 x 780 mm
-
Weight: 60 kg (depending on version)
-
Connection value/frequency: 100-240V (50/60Hz)
Objects
- All common pre-fillable packaging containers
- Additional pharmaceutical bottles and containers can be set up
Output
- 5-10 containers per minute (depending on product, container and operator)
Features of the labworx series
The groninger labworx series has the best control technology and the most sophisticated operator interface of any comparable model in the industry.
- Thanks to the software solution supplied by groninger with an HTML5-based interface, any HTML5-enabled device with the appropriate web browser can be used for operation and visualization
- groninger offers different tablets for this purpose as standard
- A flexible WLAN connection enables the operation and combination of one or more machine modules via a tablet
- All critical in-process parameters are collected
- Batch reports can be generated automatically in PDF format
- A combined batch report of the inline process steps with various machine modules can be set up
- 21 CFR Part 11 compliant
- All devices are connected to each other in the same network
- The usage parameters of the labworx machine series can be easily used on larger groninger lines.
- For the filling modules, this applies in particular to the following parameters:
- Master position
- Filling needle movement
- Needle plunge movement
- Teach-in points
- Filling volume
- The labworx portfolio covers the same processes that the high-speed lines are also able to carry out.
- The labworx series uses the same technologies as large groninger lines.
- All machine movements are servo controlled.
- Hygienic design for optimal cleaning.
- Focus on compact design and LF friendliness
This is what our customers say
Our Partners for Ready-to-use Kits
SCHOTT Pharma
adaptiQ® Fast Track Kit
Our labworx series is quickly available, and so is the appropriate ready-to-use packaging. The SCHOTT Fast Track Kits contain everything you might need to fill and close small quantities on our benchtop modules: SCHOTT vials, West stoppers and caps are all sterile, compatible and ready to use. Together with our labworx series, the SCHOTT Fast Track Kits are ideal for pharmaceutical laboratories, universities and start-ups that want to accelerate their time-to-market and offer reliability, convenience, flexibility and performance.
Stevanato Group
EZ-fill® Kit
EZ-fill® Kit is the complete high-quality packaging kit to meet your needs across the entire drug life cycle, from clinical phase to small commercial batches. Together with our labworx series, it represents the perfect solution to fill and close small quantities as well as protect, store and deliver your drug product safely. It is made of pre-sterilized containment solutions for aseptic-manufacturing available in Nest-and-Tub and Tray configurations and Ready-to-Use Add-on Components on request. labworx series and EZ-fill® Kit are the perfect match to go to the market faster and benefit from conveniency, speed and flexibility.
