labworx series

groninger benchtop machine series for filling and closing syringes, vials and cartridges.

Semi-automatic machines for filling small quantities of liquid medicines

In the research and development of medicines, in the manufacture and processing of small quantities, very specific aspects of the filling process are in the foreground.

This includes the requirements of customers and authorities (e.g. the FDA), but also very specific product properties that have direct consequences on which primary packaging materials can be used and processed. All of this is extremely important for drug development.

The groninger semi-automatic tabletop machines allow you to cover the entire filling and closing process. The labworx series uses the same technology, the same processing methods and components as the high-speed groninger filling and sealing systems. In this way, important insights and data gained during the development process can be quickly and easily scaled up to larger filling volumes and lines.

Focus on precision

When filling medicines, manufacturers and hospital pharmacies focus on the correct composition of the active ingredients and thus on safety and effectiveness. With the labworx modules, certain critical processes that are otherwise carried out manually, such as filling, can be controlled and automated. This way you are able to achieve a high and consistent level of quality in the end product.

Due to the hygienic design, laminar airflow and compact design, the machines can be safely integrated into a range of containment systems. The machines are set up with a standard batch report, compliant with 21 CFR Part 11, and thus comply with the standard regulations for the production of small batches.

labworx series

The new labworx benchtop machine portfolio consists of four standardized modules:

  • Filling module with peristaltic pump,
  • Filling module with rotary piston pump,
  • Stopper setting module and
  • Sealing module.

These series-built benchtop machines have an extremely short delivery time, allowing you to minimize your time-to-market cycle.

You will learn to appreciate the Quickconnect technology in everyday work, which enables quick set-up and, above all, quick changeover of material and formats. The labworx series offers you maximum flexibility.

Filling module with rotary piston pump

Specifications

  • Dimension L/W/H: 450 x 560 x 700 mm
  • Weight: 65 kg (depending on version)
  • Connection value/frequency: 100-240V (50/60Hz)
  • Filling range: 0.2-135ml

Options

  • Vacuum filling
  • Integration of a load cell for 100% In-Process-Control (IPC) with automatic data transfer
  • Single-use rotary piston pump
  • Stainless steel product tank

Objects

  • All common pre-fillable objects: Syringes, cartridges and vials
  • Other pharmaceutical bottles and containers can be set up

Application

  • 5-10 containers per minute (depending on product, container and operator)
LABWORX filling module with rotary piston pump (front)
LABWORX filling module with rotary piston pump (side)
LABWORX filling module with rotary piston pump (back)

Filling module with peristaltic pump

Specifications

  • Dimension: L/W/H: 450 x 510 x 700 mm
  • Weight: 50 kg (depending on version)
  • Connection value/frequency: 100-240V (50/60Hz)
  • Filling range: 0.1-250ml

Options

  • Integration of a load cell for 100% In-Process-Control (IPC)with automatic data transfer
  • Single-use Equipment
  • Stainless steel product tank

Objects

  • All common pre-fillable objects: Syringes, cartridges and vials
  • Other pharmaceutical bottles and containers can be set up

Application

  • 5-10 containers per minute (depending on product, container and operator)
groninger LABWORX filling module with peristaltic pump (front)
groninger LABWORX filling module with peristaltic pump (side))
groninger LABWORX filling module with peristaltic pump (back)

Stopper setting module

Specifications

  • Dimension L/W/H: 450 x 510 x 795 mm
  • Weight: 60 kg (depending on version)
  • Connection value/frequency: 100-240V (50/60Hz)

Options

  • Insertion tube for inserting stoppers for syringes and cartridges
  • Inserting vacuum stopper for syringes and cartridges
  • Setting tool for inserting stoppers for vials
  • Gassing for all different stoppering methods

Objects

  • All common pre-fillable objects: Syringes, cartridges and vials
  • Other pharmaceutical bottles and containers can be set up

Output

  • 5-10 containers per minute (depending on product, container and operator)
groninger LABWORX stopper setting module (front)
groninger LABWORX Stopper setting module (side)
groninger LABWORX stopper setting module (back)

Sealing module

Specifications

  • Dimensions L/W/H: 450 x 510 x 780 mm

  • Weight: 60 kg (depending on version)

  • Connection value/frequency: 100-240V (50/60Hz)

Objects

  • All common pre-fillable objects: Cartridges and vials
  • Additional pharmaceutical bottles and containers can be set up

Output

  • 5-10 containers per minute (depending on product, container and operator)
groninger LABWORX Sealing module (front)
groninger LABWORX sealing module (side)
groninger LABWORX sealing module (back)

Features of the labworx series

Human Machine Interface / Scalability / Containment systems

The groninger labworx series has the best control technology and the most sophisticated operator interface of any comparable model on the market.

  • Thanks to the software solution supplied by groninger with an HTML5-based interface, any HTML5-enabled device with the appropriate web browser can be used for operation and visualization
  • groninger offers different tablets for this purpose as standard
  • A flexible WLAN connection enables the operation and combination of one or more machine modules via a tablet
  • All critical in-process parameters are collected
  • Batch reports can be generated automatically in PDF format
  • A combined batch report of the inline process steps with various machine modules can be set up
  • 21 CFR Part 11 compliant
  • All labworx machines are connected to each other in the same network
Operation of the labworx modules via a tablet
Operation of the labworx modules via a tablet
labworx series integrated in isolator
labworx series integrated in isolator
labworx series integrated in LF
labworx series integrated in LF

This is what our customers say

The groninger labworx series helps us to develop our products and processes for our high-speed filling lines.

Bianca Bohrer
CEO, Topmedicare GmbH

Cooperation with SCHOTT Pharma for filling small quantities in vials

Our labworx series is quickly available, and so is the appropriate ready-to-use packaging. The SCHOTT Fast Track Kits contain everything you might need to fill and close small quantities on our benchtop machines: SCHOTT vials, West stoppers and caps are all sterile, compatible and ready to use. Together with our labworx series, the SCHOTT Fast Track Kits are ideal for pharmaceutical laboratories, universities and start-ups that want to accelerate their time-to-market and offer reliability, convenience, flexibility and performance.